Can a Rh negative mother have a Rh negative baby?
If the mother is Rh-negative, her immune system treats Rh-positive fetal cells as if they were a foreign substance. The mother’s body makes antibodies against the fetal blood cells. These antibodies may cross back through the placenta into the developing baby. They destroy the baby’s circulating red blood cells.
Can an Rh negative mother have a baby with Rh positive?
If a woman who is Rh negative and a man who is Rh positive conceive a baby, the fetus may have Rh-positive blood, inherited from the father. (About half of the children born to an Rh-negative mother and Rh-positive father will be Rh-positive.)

Do both parents have to be Rh negative to have a Rh negative child?
Each person has two Rh factors in their genetics, one from each parent. The only way for someone to have a negative blood type is for both parents to have at least one negative factor. For example, if someone’s Rh factors are both positive, it is not possible for his or her child to have a negative blood type.
What would happen if the mom has a negative blood type and the baby has a positive blood type?
If the Rh negative mother has been sensitized to Rh positive blood, her immune system will make antibodies to attack her baby. When the antibodies enter your baby’s bloodstream, they will attack the red blood cells, causing them to break down. This can lead to problems. This condition can be prevented.
What happens when baby and mom have different blood types?
If a baby’s and mother’s blood are incompatible, it can lead to fetal anemia, immune hydrops (erythroblastosis fetalis) and other complications. The most common type of blood type incompatibility is Rh disease (also known as Rh incompatibility). The Rh factor is a protein on the covering of red blood cells.

Do I need a RhoGAM shot for second pregnancy?
When is a RhoGAM shot administered? For a first pregnancy, RhoGAM is typically injected at about 28 weeks and then again within 72 hours post-delivery. For any subsequent pregnancies, RhoGAM is administered regularly during the second half of the pregnancy.
Can mom and baby have same blood type?
While a child could have the same blood type as one of his/her parents, it doesn’t always happen that way. For example, parents with AB and O blood types can either have children with blood type A or blood type B. These two types are definitely different than parents’ blood types!