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What drugs interact with brimonidine?

What drugs interact with brimonidine?

Some products that may interact with this drug include: beta-blockers (such as atenolol, metoprolol, timolol eye drops), digoxin, high blood pressure medications (such as clonidine, terazosin), tricyclic antidepressants (such as amitriptyline).

Who should not take brimonidine?

Brimonidine is also contraindicated in patients with hypersensitivity to any component of the medication, and it should not be used in children under the age of 2 because there have been reports of apnea, bradycardia, hypothermia, hypotonia, lethargy, and unresponsiveness in infants receiving brimonidine treatment ( …

What are the side effects of brinzolamide?

5. Side effects of brinzolamide

  • an itchy or painful eye and a feeling that something’s in your eye, blurred vision, or watery eyes.
  • your eyes become sensitive to bright light (photophobia)
  • a bad or unusual taste in your mouth.

What are contraindications for administering timolol?

Who should not take TIMOLOL MALEATE?

  • overactive thyroid gland.
  • diabetes.
  • low blood sugar.
  • myasthenia gravis, a skeletal muscle disorder.
  • complete heart block.
  • partial heart block.
  • sinus bradycardia.
  • sudden and serious symptoms of heart failure called acute decompensated heart failure.

Does brimonidine affect the heart?

Blood pressure and heart rate decreased significantly in the brimonidine group compared with placebo.

Does brimonidine contain beta blockers?

Combigan (brimonidine tartrate/timolol maleate ophthalmic solution) is a combination of an alpha agonist and a beta-blocker that work to reduce pressure inside the eye used to treat glaucoma or ocular hypertension (high pressure inside the eye).

Can brimonidine cause heart problems?

This medicine may cause heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort, dilated neck veins, extreme fatigue, irregular breathing, an irregular heartbeat, shortness of breath, swelling of the face, fingers, feet, or lower legs, weight gain, or wheezing.

Does brinzolamide lower blood pressure?

Azopt contains the active drug brinzolamide. It belongs to a class of drugs called carbonic anhydrase inhibitors. (A class of drugs is a group of medications that work in a similar way.) Azopt works to decrease pressure inside your eye by reducing the amount of fluid the eye naturally produces.

Is brinzolamide a beta blocker?

Alcon announced that the FDA has approved Simbrinza (brinzolamide/brimonidine tartrate) Suspension indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

When is atropine contraindicated?

Atropine generally is contraindicated in patients with glaucoma, pyloric stenosis, thyrotoxicosis, fever, urinary tract obstruction and ileus.

Why is timolol contraindicated in asthma?

International guidelines recommend that beta‐blockers are contraindicated in asthma over safety concerns regarding acute bronchoconstriction 1, 2, 3. This effect results from endogenous and exogenous catecholamine antagonism at the pulmonary beta2‐adrenoceptor leading to unopposed cholinergic tone.

Does brimonidine lower heart rate?

What are the contraindications for Brinzolamide?

Brinzolamide is contraindicated in patients with hypersensitivity to any component of the product. Also, brinzolamide is a chemical sulfonamide possessing a structure and pharmacologic activity distinct from the bacteriostatic sulfonamides. Rarely, sulfonamides of any type can produce allergic reactions, some of which may be severe.

What are the contraindications for nitroglycerin?

A known history of increased intracranial pressure, severe anemia, right-sided myocardial infarction, or hypersensitivity to nitroglycerin are all contraindications to nitroglycerin therapy. Click to see full answer. Likewise, when should you not take nitroglycerin?

Why is Brinzolamide ophthalmic suspension not recommended in patients with angle-closure glaucoma?

Because brinzolamide ophthalmic suspension and its metabolite are excreted predominantly by the kidney, brinzolamide ophthalmic suspension is not recommended in such patients. The management of patients with acute angle-closure glaucoma requires therapeutic interventions in addition to ocular hypotensive agents.

What should I know before taking Brinzolamide?

Tell all of your health care providers that you take brinzolamide. This includes your doctors, nurses, pharmacists, and dentists. Use care when driving or doing other tasks that call for clear eyesight. If you have a sulfa (sulfonamide) allergy, talk with your doctor. Have your eye pressure and eyesight checked as you have been told by the doctor.