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What is juvenile angiofibroma?

What is juvenile angiofibroma?

Juvenile angiofibroma (JA) is a rare benign vascular lesion of the skull base that affects young adolescent males. The management of JA is challenged by the abundant vascular blood supply of the lesion, along with the complex anatomy of the skull base and the young age of the affected population.

Will Angiofibroma grow back?

In up to 50 percent of cases, nasopharyngeal angiofibroma will regrow after being surgically removed. Regrowth usually occurs within two years following surgery, most often because a piece of the tumor was left behind.

Is juvenile angiofibroma malignant?

Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascular tumor that appears in the nasal cavity. Although it is non-malignant (not cancerous), it can expand quickly and extensively.

How common is Angiofibroma?

Juvenile nasopharyngeal angiofibroma is the most common benign tumor of the nasopharynx, but has a relatively low incidence. It accounts for only 0.5 percent of all head and neck tumors.

How is Angiofibroma removed?

Angiofibromas can be safely & effectively removed by shave excision or electrosurgery, and less commonly using liquid nitrogen. Do not attempt self-removal of angiofibromas as that can often lead to permanent scars.

Can angiofibromas be removed?

Although angiofibromas are benign, they are persistent. Angiofibromas can be removed for cosmetic or pain-related reasons. The recurrence rate for angiofibromas associated with tuberous sclerosis may be as high as 80% [1].

How do you treat angiofibromas on face?

Current treatment options for facial angiofibromas include destructive approaches such as dermabrasion, surgical excision, and laser therapy. A more targeted therapeutic approach is needed because current therapies are not effective in preventing early lesions and therefore may have less than satisfactory outcomes.

How do you get angiofibroma?

What causes angiofibromas? Angiofibromas are caused by a local overgrowth of collagen, fibroblasts, and blood vessels. In tuberous sclerosis, mutations are present in tuberous sclerosis complex 1 (TSC1), which encodes the protein hamartin, and tuberous sclerosis complex 2 (TSC2) which encodes the protein tuberin.

How is angiofibroma removed?

What is juvenile angiofibroma (ja)?

Juvenile angiofibroma (JA) is a benign, highly vascular tumor which is diagnosed on the basis of clinical and imaging features. It has a characteristic pattern of spread commonly involving the pterygopalatine fossa and pterygoid base. The mainstay of treatment is surgery, while radiotherapy is rarely used for the treatment of recurrent lesion.

Is endoscopic surgery the best treatment for juvenile angiofibroma?

Endoscopic endonasal surgery is currently the treatment of choice for small to intermediate size JAs, and is feasible even for advanced lesions; however, this should only be practiced in well-experienced centers. Keywords: juvenile angiofibroma, endoscopic surgery, surgical treatment of juvenile angiofibroma Introduction

What is the pathophysiology of juvenile nasopharyngeal angiofibroma (JNA)?

Early stage juvenile nasopharyngeal angiofibroma (JNA) has a distinct blood supply from the ipsilateral ECA, most commonly the internal maxillary artery, ascending pharyngeal, sphenopalatine artery, and descending palatine artery, which can easily be embolized.