What is the most common cause of thrombocytopenia?
Autoimmune disease which causes ITP. ITP is sometimes associated with other autoimmune conditions such as lupus. Bone marrow diseases, including aplastic anemia, leukemia, certain lymphomas and myelodysplastic syndromes. Cancer treatments like chemotherapy and radiation therapy.
Which antibiotics can cause thrombocytopenia?
Medicines Known to Cause DITP
| Medicine Classification | Examples of Implicated Medicines |
|---|---|
| Antibiotics | Cephalosporins, linezolid, penicillins, sulphonamides, trimethoprim, vancomycin |
| Antimalarials | Quinine |
| Antimycobacterials | Ethambutol, rifampicin |
| Antiepileptics | Carbamazepine, phenytoin, sodium valproate |
What anticoagulant drug can cause thrombocytopenia?
Medications Associated With Heparin-Induced Thrombocytopenia
| Medication Name, Generic (Trade) | Therapeutic Class of Anticoagulant |
|---|---|
| Argatroban (Argatroban) | Direct thrombin inhibitor |
| Bivalirudin (Angiomax) | Direct thrombin inhibitor |
| Fondaparinux (Arixtra) | Factor Xa inhibitor |
| Warfarin (Coumadin) | Vitamin K antagonist |
What drugs are contraindicated with thrombocytopenia?
Which medications are contraindicated in the treatment of immune thrombocytopenia (ITP) during pregnancy?
- Cyclosporine.
- Dapsone.
- Thrombopoietin receptor agonists.
- Alemtuzumab.
- Rituximab.
Can antibiotics cause thrombocytopenia?
Antibiotic-induced immune thrombocytopenia (AIT) is a rare postoperative complication that can develop after the use of commonly used antibiotics in total joint arthroplasty.
Can warfarin cause thrombocytopenia?
Warfarin may cause microthrombosis in patients with HIT. These patients typically present with an international normalized ratio (INR) greater than 4, which corresponds to severe protein C depletion. Initiation of warfarin should be postponed until substantial platelet recovery.
What is the most common drug-induced thrombocytopenia in hospitalized patients?
Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia. If a medicine prevents your bone marrow from making enough platelets, the condition is called drug-induced nonimmune thrombocytopenia.
Does ceftriaxone cause thrombocytopenia?
Ceftriaxone causes drug-induced immune thrombocytopenia and hemolytic anemia: characterization of targets on platelets and red blood cells. Transfusion.
Does warfarin cause thrombocytopenia?
The risk of developing warfarin-induced skin necrosis (WISN) with warfarin is reported to be <1%. However, the risk of WISN may be increased with the initiation of warfarin in the setting of heparin-induced thrombocytopenia and thrombosis syndrome (HITT).
Does rivaroxaban cause thrombocytopenia?
A diagnosis of rivaroxaban-induced thrombocytopenia was made. The incidence of thrombocytopenia due to NOACs is rare. Careful attention to thrombocytopenia, which is associated with a higher risk for life-threatening bleeding, is therefore necessary during treatment with NOACs.
What medications cause thrombocytosis?
Substances
- Anti-Bacterial Agents.
- Lactams.
- Vinca Alkaloids.
- Miconazole. Iron.
How is drug-induced thrombocytopenia diagnosed?
Specialized laboratory diagnostic tests have been developed and are helpful to confirm the diagnosis. Treatment of DITP involves discontinuation of the offending drug. The platelet count usually starts to recover after 4 or 5 half-lives of the responsible drug or drug metabolite.
Which drugs cause the most harm?
Acetaminophen (Tylenol)
What drugs cause high body temperature?
– zinc supplements and other zinc-containing drugs – certain antidepressants, including desipramine (Norpramin) and nortriptyline (Pamelor) – hormonal medications – antibiotics – pain relievers – heart and blood pressure drugs
What drugs can cause complications?
Antibiotics,such as nitrofurantoin and sulfa drugs
Does metoprolol cause thrombocytopenia?
Thrombocytopenia is found among people who take Metoprolol succinate, especially for people who are male, 60+ old, have been taking the drug for < 1 month. The phase IV clinical study analyzes which people take Metoprolol succinate and have Thrombocytopenia. It is created by eHealthMe based on reports of 44,206 people who have side effects when taking Metoprolol succinate from the FDA, and is updated regularly.