What is the prognosis of agenesis of corpus callosum?
Agenesis of the corpus callosum, a brain defect present at birth, can be mild or severe. It’s usually not fatal, and specific therapies can help. Although the disorder is generally diagnosed in the first two years of life, some cases are diagnosed later.
What are the consequences of agenesis of the corpus callosum?
The effects of the disorder range from subtle or mild to severe, depending on associated brain abnormalities. Children with the most severe brain malformations may have intellectual impairment, seizures, hydrocephalus, and spasticity.
Is agenesis of the corpus callosum progressive?
Hereditary motor and sensory neuropathy with agenesis of the corpus callosum (HMSN/ACC), a neurodevelopmental and neurodegenerative disorder, is characterized by severe progressive sensorimotor neuropathy with resulting hypotonia, areflexia, and amyotrophy, and by variable degrees of dysgenesis of the corpus callosum.
What is the common symptom associated with agenesis of the corpus callosum?
An abnormally small head (microcephaly), or sometimes an unusually large head (macrocephaly), may be present. Tags of skin in front of the ears (pre-auricular skin tags), one or more bent fingers (camptodactyly), and delayed growth have also been associated with some cases of agenesis of corpus callosum.
Can you live a normal life without a corpus callosum?
While not essential for survival, a missing or damaged corpus callosum can cause a range of developmental problems. It’s thought that one in 3,000 people have agenesis of the corpus callosum—a congenital disorder that sees a complete or partial absence of the conduit.
Is corpus callosum a disability?
Children with disorders of the corpus callosum have a range of learning abilities and disabilities. The level of difficulty depends on the number of brain structure problems and the presence of other syndromes. Some children have mild learning problems. Others have severe intellectual disabilities.
Is agenesis of the corpus callosum a disability?
Corpus callosum agenesis or dysgenesis (CCA) can be diagnosed antenatally, either isolated or associated with other cerebral or extra-cerebral malformations….Corpus Callosum Agenesis and Intellectual Disability (ACCREM)
| Last Update Posted: | June 19, 2014 |
| Last Verified: | June 2014 |
Can you function without a corpus callosum?
People born without a corpus callosum face many challenges. Some have other brain malformations as well—and as a result individuals can exhibit a range of behavioral and cognitive outcomes, from severe cognitive deficits to mild learning delays.
Is agenesis of corpus callosum a disability?
Corpus callosum agenesis or dysgenesis (CCA) can be diagnosed antenatally, either isolated or associated with other cerebral or extra-cerebral malformations….Corpus Callosum Agenesis and Intellectual Disability (ACCREM)
| Observational Model: | Cohort |
| Time Perspective: | Prospective |