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Which is better clomiphene or letrozole?

Which is better clomiphene or letrozole?

Most studies conclude that even if clomid is as effective at helping someone achieve pregnancy, letrozole is usually the better choice due to fewer side effects and risks. Letrozole can often be used for those who tried Clomid unsuccessfully and are considered “Clomid resistant.”

How successful is letrozole for infertility?

In more recent studies, letrozole has shown higher rates of live birth compared to clomiphene. Close to 28% of people with PCOS taking letrozole in one study successfully got pregnant and had a baby, compared to about 19% of those taking clomiphene.

Can letrozole cause twins?

The risk of twins with letrozole is estimated to be approximately 3-5%, which appears to be lower than the risk of twins with clomiphene citrate (7-8%), but is still higher than the risk of twins in a spontaneous pregnancy (2-3%). Although triplets and higher-order pregnancies are rare, these may occur <1% of the time.

How do I know if letrozole is working?

How will I know if Letrozole is working? You may be asked to have a blood test during the menstrual cycle in which you are taking Letrozole. We usually take this blood sample on day 21 of your menstrual cycle and measure levels of the female hormone called progesterone. A level of 30 nmol/L or more is a good result.

How many cycles does it take to get pregnant?

60 percent get pregnant within three cycles (about three months). 80 percent get pregnant within six cycles (about six months). 85 percent get pregnant within 12 cycles (about one year). 92 percent get pregnant within 48 cycles (about four years).

How many cycles of letrozole did it take to get pregnant?

The average time to become pregnant in the group taking letrozole was 90 days, or about 3 cycles. About 28% of women taking letrozole resulted in a live birth in the study. Letrozole is a drug in the class of medications called aromatase inhibitors.

How fast do follicles grow on Femara?

In natural cycles, follicles grow at an average of 0.6 mm/day from 2 to 5 mm in diameter, 1 mm/day from 5 to 10 mm in diameter, and 1.2 mm/day from 10 to 16 mm in diameter. Pre-ovulatory follicles (> 14 mm) grow at a rate of 1.5 to 2 mm/day [68].