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Can hypertension cause renal cell carcinoma?

Can hypertension cause renal cell carcinoma?

Hypertension proved to be a strong and independent risk factor for kidney cancer mortality. Smokers with systolic blood pressure above 160 mm Hg had a risk of renal cell carcinoma that was 8 times higher than for those with a blood pressure of less than 120 mm Hg.

Which of the following signs and symptoms represents the classic triad of renal carcinoma?

Signs and symptoms Renal cell carcinoma may remain clinically occult for most of its course. Only 10% of patients present with the classic triad of flank pain, hematuria, and flank mass. Other signs and symptoms include the following: Weight loss.

What is the most common presenting symptom of renal cell carcinoma?

Patients with localized disease can present with a wide array of symptoms and/or laboratory abnormalities, or they may be diagnosed incidentally. In one review of 309 consecutive patients with RCC, the most common presenting symptoms were hematuria, abdominal mass, pain, and weight loss [2].

Which issue is considered a paraneoplastic syndrome that is common in patients with renal cell carcinoma?

Hypercalcemia is the most common of the paraneoplastic syndromes in patients with RCC and of those with hypercalcemia and RCC, approximately 75% have high-stage lesions.

What are the causes of secondary hypertension?

Secondary hypertension is high blood pressure caused by another condition or disease. Conditions that may cause secondary hypertension include kidney disease, adrenal disease, thyroid problems and obstructive sleep apnea.

What is Stauffer syndrome?

Stauffer Syndrome (SS) is a paraneoplastic disorder associated with renal cell carcinoma (RCC). First described by Herbert Maurice Stauffer in 1961, it is characterized by hepatic dysfunction in the absence of metastasis, and elevated alkaline phosphatase, aminotransferases and prolonged prothrombin time.

How is renal cell carcinoma detected?

CT scan, a test that uses a powerful X-ray to make detailed pictures inside your body. Nephrectomy, when doctors remove part of one of your kidneys, or sometimes the whole kidney, to check it for renal cell carcinoma. You’ll have this test if your doctor has already spotted a tumor, but doesn’t know if it’s cancer.

Can hypertension cause kidney?

It also can cause swelling, or edema, in your legs or other areas of your body. High blood pressure is one of the major causes of chronic kidney disease. And kidney disease can also cause high blood pressure. No matter which came first, having high blood pressure damages the tiny blood vessels in the kidneys.

What are paraneoplastic syndromes?

Paraneoplastic syndromes of the nervous system are a group of uncommon disorders that develop in some people who have cancer. Paraneoplastic syndromes can also affect other organ systems including hormones (endocrine), skin (dermatologic), blood (hematologic) and joints (rheumatologic).

What is the treatment for malignant hypertension (high blood pressure)?

Initially, patients treated for malignant hypertension are instructed to fast until stable. Once stable, all patients should obtain good long-term care of their hypertension, including a diet that is low in salt. If indicated, the patient should follow a diet that can induce weight loss.

What does genome scan data tell us about blood pressure phenotypes?

Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the framingham heart study. Hypertension. 2000 Oct. 36 (4):477-83. [Medline].

Is there a gene for blood pressure on chromosome 17?

Levy D, DeStefano AL, Larson MG, et al. Evidence for a gene influencing blood pressure on chromosome 17. Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the framingham heart study. Hypertension. 2000 Oct. 36 (4):477-83. [Medline]. Coffman TM.