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What is ICG used for?

What is ICG used for?

Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, liver and gastric blood flow, and for ophthalmic angiography.

What is ICG in laparoscopy?

Background. Bile duct injury is the most feared complication during laparoscopic cholecystectomy. Real-time intraoperative imaging using indocyanine green (ICG) might reduce the risk of bile duct injury by improving visualization of the biliary tree during laparoscopic cholecystectomy.

How long does indocyanine green stay in your system?

After being injected, indocyanine green (ICG) stays in the tissues for up to 20 to 30 minutes. This longer duration is because ICG binds tightly to plasma proteins, which confines it to the vascular system. ICG stays longer in tissues with higher blood flow, such as the blood vessels of the retina and the choroid.

What is a ICG test?

Indocyanine Green Angiography (ICG) is a diagnostic procedure that uses ICG dye to examine the blood flow in the CHOROID – the layer of blood vessels which lies underneath the retina. Indocyanine Green dye is injected into a vein in the arm/hand.

How do you inject ICG?

ICG administration is to be performed via a central or peripheral venous line. Inject the prepared dose of ICG solution into the central or peripheral line as a tight bolus and immediately followed by a bolus of 10-12 mL of normal saline for injection.

Does ICG contain iodine?

ICG contains sodium iodide and, according to the manufacturer, it should be used with caution in patients who have a history of allergy to iodides because of the risk of anaphylaxis.

How is ICG metabolized?

The ICG is not metabolized; it does not undergo enterohepatic recirculation. Thus, ICG excretion rate in bile reflects the hepatic excretory function and hepatic energy status.

Does indocyanine green contain iodine?

Because indocyanine green contains iodine, the iodine-binding capacity of thyroid tissue may be reduced for at least 1 week after indocyanine green administration. Do not perform radioactive iodine uptake studies for at least 1 week after the administration of indocyanine green.

What is ICG test for heart?

Impedance Cardiography (ICG) is a non-invasive technology that measures the total electrical conductivity of the thorax, the area between the neck and the abdomen. The test measures changes over a continuous period to record data such as heart rate, cardiac output, ventricular ejection time, and stroke volume.

What is heart ICG?

Impedance cardiography (ICG) is a non-invasive technology measuring total electrical conductivity of the thorax and its changes in time to process continuously a number of cardiodynamic parameters, such as stroke volume (SV), heart rate (HR), cardiac output (CO), ventricular ejection time (VET), pre-ejection period and …

Can you mix ICG with saline?

ICG must be used within 6 hours after reconstitution. A 3 mL (7.5 mg) dose, followed by a 10 mL bolus of saline, is recommended. Multiple doses can be administered as required.

What is the role of ICG in colorectal surgery?

In colorectal surgery the peri-tumoral injection of ICG can be used to study lymphatic mapping that might be interesting in case of right sided tumors, known to have highly variable lymphatic drainage [49] or for sentinel lymph nodes biopsy in early stage rectal cancers [50].

How much ICG do you give a patient?

As concerns the exact dose and concentration of ICG to be given to patients, most authors use 0.2–0.5 kg body weight [13, 34]. Morita et al. [35] used 2.5 mg but did not state the dilution or the volume.

How can we use ICG excreted by the bile?

Discussion Since ICG is excreted virtually unchanged by the bile, the most obvious application is the visualization of the biliary tree.

What is the role of ICG in the diagnosis of ischemic parenchyma?

ICG can be used both to clarify the vascular anatomy as well as to identify ischemic parenchyma in various clinical situations.