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What is the indication of metolazone?

What is the indication of metolazone?

Metolazone tablets are indicated for the treatment of salt and water retention including: edema accompanying congestive heart failure; edema accompanying renal diseases, including the nephrotic syndrome and states of diminished renal function.

When should metolazone be administered?

Metolazone is recommended to be taken in the morning due to its prolonged absorption and duration of action. In patients resistant to loop diuretics, metolazone should be given one hour before the regular morning dose of furosemide.

What is the difference between metolazone and Lasix?

Lasix (furosemide) and Zaroxolyn (metolazone) are diuretics (water pills) used treat excess accumulation of fluid or swelling of the body (edema) and high blood pressure (hypertension). Lasix is a brand name for furosemide. Zaroxolyn is a brand name for metolazone.

What are side effects of metolazone?

Metolazone, Oral Tablet. Metolazone oral tablet is available as both a generic and brand-name drug. Brand name: Zaroxolyn. The most common side effects of metolazone are constipation, dry mouth, diarrhea, headache, stomach pain, and blurred vision.

Does metolazone cause hyponatremia?

Metolazone was strongly associated with hyponatremia, hypokalemia, and worsening renal function (P<0.0001 for all) with minimal effect attenuation following covariate and propensity adjustment.

Can I take furosemide and metolazone together?

Even at low doses metolazone significantly potentiates the diuretic effects of furosemide and therefore simplifies the treatment of fluid retention. High doses of furosemide can be avoided in many cases, a factor of particular advantage in ambulatory long term therapy and in patients with decreased kidney function.

Does metolazone lower blood pressure?

Metolazone is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps to lower blood pressure . This medicine is available only with your doctor’s prescription .

Does metolazone lower potassium?

Metolazone can reduce blood potassium and magnesium levels. This is especially true in patients who also are taking “loop” diuretics such as furosemide (Lasix), bumetanide (Bumex), and torsemide (Demadex ).

Can you take metolazone and furosemide together?

furosemide metOLazone Before taking furosemide, tell your doctor if you also use metOLazone. You may need dose adjustments or special tests in order to safely take both medications together. This combination may lower levels of certain minerals in your body such as potassium, magnesium, and sodium.

Does metolazone affect heart rate?

Check with your doctor right away if you have any of the following symptoms while taking this medicine: convulsions or seizures; decreased urine; drowsiness; dry mouth; excessive thirst; muscle pains or cramps; nausea or vomiting; increased heart rate or pulse; or unusual tiredness or weakness.