What is non endemic goiter?
A nontoxic goiter is a diffuse or nodular enlargement of the thyroid gland that does not result from an inflammatory or neoplastic process and is not associated with abnormal thyroid function.
What is nontoxic Uninodular goiter?
Nontoxic multinodular goiter (MNG) is a disease of the thyroid gland characterized by the presence of thyroid nodules (dominant focal structural lesions) without biochemical abnormalities of the thyroid gland.
What is the difference between toxic and non-toxic goitre?
Examples of toxic goiters include diffuse toxic goiter (Graves disease), toxic multinodular goiter, and toxic adenoma (Plummer disease). Nontoxic goiter: A goiter without hyperthyroidism or hypothyroidism is described as a nontoxic goiter.
Can a nontoxic multinodular goiter be cancerous?
Multinodular goiters (MNG) have recently been shown to have an incidence of cancer that approaches that of solitary thyroid nodule. However, fine needle aspiration (FNA) of a MNG is limited due to the presence of multiple nodules.
What causes a non toxic goiter?
Simple nontoxic goiter is noncancerous enlargement of the thyroid gland that does not involve over- or underproduction of thyroid hormones. Noncancerous thyroid enlargement can occur because of lack of iodine in the diet or ingestion of certain substances or drugs. People often have no symptoms.
What causes a nontoxic goiter?
Abnormalities of iodine supplies or metabolism always lead to nontoxic goiter. The thyroid gland secretes thyroid hormones (Thyroxin/T4 and triiodothyronine/T3) in response to thyrotropic hormone (TSH) of the pituitary gland stimulation. They are important for body cells’ metabolism.
How do you shrink a nontoxic goiter?
Of patients with nontoxic diffuse goiter treated with radioactive iodine, 90% have an average of 50-60% reduction in goiter volume after 12-18 months, with a reduction in compressive symptoms. The decrease in goiter size has positively correlated with the dose of iodine-131 (131 I).