Why DMSO-d6 NMR peak?
As dmso is highly miscible with water, during handling DMSO-d6 absorbs moisture and the peak at 3.33 is due to the moisture present. If the DMSO-d6 is being used for long time, usually the water peak comes bigger than the residual solvent peak in NMR.
Where does DMSO show up on 13C NMR?
Does dimethylsulfoxide 13C NMR give rise to additional signals in addition to the major signal at 39,7ppm? The 13C NMR for dimethylsulfoxide shows a signal at 39.7ppm, but we observed additional signals with low intensities.
Why DMSO gives Septet in 13C NMR?
D is NMR-active and bear a magnetic moment I = 1. Applying the rule “2NI+1” for the multiplicity, one gets 2·3·1+1 = 7 (the CD3 groups are equivalent). That’s why DMSO-d6 gives a septet centered at 39.52 ppm.
Why is DMSO used in NMR?
Deuterated dimethylsulfoxide (d6-DMSO) is one of the most commonly used NMR solvents, in part due to its ability to dissolve compounds with poor solubility in other common NMR solvents.
How do you make d6 DMSO?
Deuterated DMSO is produced by heating DMSO in heavy water (D2O) with a basic catalyst such as calcium oxide. The reaction does not give complete conversion to the d6 product, and the water produced must be removed and replaced with D2O several times to drive the equilibrium to the fully deuterated product.
Is DMSO a strong base?
SN2 REACTIONS As a random example, consider a general primary alkyl halide reacting with NaOH in DMSO (dimethylsulfoxide): OH− is small, so it is fast, and therefore, it is a good nucleophile. It also is quite a strong base.
What is the NMR spectrum of DMSO d6?
13 C NMR Spectrum of DMSO- d6 Pure deuterated DMSO shows no peaks in 1 H NMR spectroscopy and as a result is commonly used as an NMR solvent. However commercially available samples are not 100% pure and a residual DMSO-d 5 1 H NMR signal is observed at 2.50ppm (quintet, J HD =1.9Hz). The 13 C chemical shift of DMSO-d 6 is 39.52ppm (septet).
What is the 13C chemical shift of DMSO-d6?
The 13 C chemical shift of DMSO-d 6 is 39.52ppm (septet). ^ Fruhstorfer, Wolfgang; Hampel, Bruno, (E. Merck A.-G.); 1964; “Hexadeuterodimethyl sulfoxide.”; DE 1171422 (B)
Is Deuterated DMSO a good NMR solvent?
Pure deuterated DMSO shows no peaks in 1H NMR spectroscopy and as a result is commonly used as an NMR solvent. However commercially available samples are not 100% pure and a residual DMSO-d 5 1H NMR signal is observed at 2.50ppm (quintet, J HD=1.9Hz).
What is the chemical name of deuterated DMSO?
From Wikipedia, the free encyclopedia Deuterated DMSO, also known as dimethyl sulfoxide-d6, is an isotopologue of dimethyl sulfoxide (DMSO, (CH 3) 2 S=O)) with chemical formula ((CD 3) 2 S=O) in which the hydrogen atoms (“H”) are replaced with their isotope deuterium (“D”). Deuterated DMSO is a common solvent used in NMR spectroscopy.